pyrP [2017-8-11 16:0:3]

uracil permease

Locus: BSU15480

Isoelectric point: 9.50

Molecular weight: 45.41 kDa

Protein length: 434 aa

Gene length: 1302 bp

Function: uracil transport in/out via proton symport

Product: uracil permease

Essential: no

Synonyms

Genomic Context

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Categories containing this gene/protein

• Cellular processes → Transporters → Transporters/ other → Nucleotide/ nucleoside transporter
• Metabolism → Nucleotide metabolism → Biosynthesis/ acquisition of nucleotides → Biosynthesis/ acquisition of pyrimidine nucleotides
• Groups of genes → Membrane proteins

Gene

Coordinates: 1,619,023 → 1,620,330

The protein

Protein family

• xanthine/uracil permease family (according to Swiss-Prot)

Structure

• 3QE7 (E. coli uracil transporter, 43% identity) PubMed

Localization

• cell membrane PubMed

Expression and Regulation

Operons

• Genes: pyrR-pyrP-pyrB-pyrC-pyrAA-pyrAB-pyrK-pyrD-pyrF-pyrE
  Description: PubMed

  Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon

  Regulatory mechanism

  • PyrR: termination/ antitermination, via RNA switch, in PyrR regulon

  Regulation

  • induced in the absence of uridine nucleotides (PyrR) PubMed

References

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